There are some policy prescriptions that could lower that toll, but some other politically popular ones would likely increase it.

Even as a California safer injection site bill approaches final passage, the Justice Department takes aim at the harm reduction practice; state financial regulators want Congress to act on marijuana banking, and more.

An Arizona prosecutor gets challenged for trying to profit off small-time pot offenders, Oregon regulators slash the daily purchase amounts for medical marijuana patients, a Louisiana prisoner featured in the Chronicle years ago gets a break, and more.

New polls in New Jersey and Wisconsin show solid support for marijuana legalization, Chicago harm reduction pioneer Dan Big has died too early, the FDA approves clinical trials of psilocybin for treatment-resistant depression, an Ohio drug defelonization initiative is on the November ballot, and more.

The cofounder of the Chicago Recovery Alliance and pioneer of naloxone for overdose reversal passed unexpectedly this week at age 59.

The pro-Duterte forces have noticed our efforts to stop his killing campaign.

It isn't the Wild West anymore.

Oklahoma continues to grapple with its new medical marijuana program, Utah foes try a novel strategy to block a medical marijuana initiative, and more.

Louisiana doctors could soon treat more medical marijuana patients, black VA patients on opioid therapy are more likely to be drug tested and have their treatment halted for illicit drug use than whites, a Georgia judge throws out a heroin murder conviction, and more.